Publications/References | Luxcel Biosciences
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Monitoring Intracellular Oxygen Concentration: Implications for Hypoxia Studies and Real-Time Oxygen Monitoring. Potter M et al, Oxygen Transport to Tissue XXXVII, Advances in Experimental Medicine and Biology, 2016; 876: 257 - 63

Sommakia S, et al. (Mitochondrial cardiomyopathies feature increased uptake and diminished efflux of mitochondrial calcium. Journal of Molecular and Cellular Cardiology. (Epub ahead of print)

In vitro analysis of cell metabolism using a long-decay pH-sensitive lanthanide probe and extracellular acidification assay. Hynes J et al., Analytical Biochemistry, 2009; 390: 21-28.
High-Throughput Real-Time Analysis of Cell Oxygenation Using Intracellular Oxygen-Sensitive Probes. Hynes and Carey Mitochondrial Medicine 1, Probing Mitochondrial Function, Methods in Molecular Biology, 2015; 1264: 203 - 217.
Fluorescence-Based Microplate Assays for In Vitro Assessment of Mitochondrial Toxicity, Metabolic Perturbation, and Cellular Oxygenation. Hynes J et al., Curr. Protoc. Toxicol., 2016 May; Chapter 2: Unit 2.16.

Ma D, et al. (2017) Exploiting mitochondrial and oxidative vulnerabilities with a synthetic analog of pancratistatin in combination with piperlongumine for cancer therapy. The FASEB Journal. (Epub ahead of print)

Correia C, et al. (2017) Distinct carbon sources affect structural and functional maturation of cardiomyocytes derived from human pluripotent stem cells. Scientific Reports 7:8590.

Chapple, S. J., et al. (2016). "Bach1 differentially regulates distinct Nrf2-dependent genes in human venous and coronary artery endothelial cells adapted to physiological oxygen levels." Free Radical Biology and Medicine 92: 152-162.

Abdul-Ghani M, et al. (2017) Cardiotrophin 1 stimulates beneficial myogenic and vascular remodeling of the heart. Cell Res. Epub ahead of print

Cancer Cell Mitochondria Targeting by Pancratistatin Analogs is Dependent on Functional Complex II and III. Ma D et al. Sci. Rep., 2017; 7: 42957.
Analysis of mitochondrial function using phosphorescence oxygen sensitive probes. Will Y et al. Nature Protocols. 2007; 1(6): 2563-2572.
A high-throughput dual parameter assay for assessing drug-induced mitochondrial dysfunction provides additional predictivity over two established mitochondrial toxicity assays. Hynes J et al. Toxicol. In Vitro, 2012 Mar; 27(2): 560-569.

Jiang H, et al. (2017) Nutrient sensing and metabolic changes after methionine deprivation in primary muscle cells of turbot (Scophthalmus maximus L.). The Journal of Nutritional Biochemistry. Epub ahead of print